Application

SnAP Reagents provide a one-step route, in tandem with various aldehyde substrates, to saturatedN-heterocycles. The synthesis ofN-heterocycles through SnAP Reagents requires mild reaction conditions, and aldehydes bearing aryl, heteroaryl,glyoxyl,aliphatic, and halogenated groups are well tolerated. This product was introduced in collaboration with theBode Research Group

SnAP 3-Spiro-(4-Pip) M Reagent may be used in the preparation of unprotected, saturated N-heterocyclic compounds.

General description

SnAP (Sn amino protocol) reagents have been developed by Professor Dr. Jeffrey Bode and co-workers. (These reagents are useful for the preparation of medium-ring (6-9 membered) saturated N-heterocycles, including bicyclic and spirocyclic structures.) SnAP reagents are stable and easy to handle in laboratories. They can be prepared from simple raw materials.

Other Notes

Technology spotlight: SnAP Reagents Professor product portal: Jeffrey Bode Research GroupSnAP Reagents for the Synthesis of Piperazines and MorpholinesSnAP reagents for the one-step synthesis of medium-ring saturated N-heterocycles from aldehydesSnAP Reagents for a Cross-Coupling Approach to the One-Step Synthesis of Saturated N-HeterocyclesBespoke SnAP Reagents for the Synthesis of C-Substituted Spirocyclic and Bicyclic Saturated N-Heterocycles

Packaging

500 mg in glass bottle